Olaparib, CAS [[763113-22-0]]

Product Overview

• Article Name: Olaparib, CAS [[763113-22-0]]
• Biozol Catalog Number: FBM-10-2154
• Supplier Catalog Number: 10-2154
• Alternative Catalog Number: FBM-10-2154-5MG,FBM-10-2154-25MG,FBM-10-2154-10MM/1MLDMSO
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: AZD-2281, KU-59436

Product Description

PARP1 inhibitor

Product Properties

• Molecular Weight: 434.47
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [763113-22-0]
• Formula: C24H23FN4O3

Application Notes

• Application Notes: A highly potent and selective PARP-inhibitor with IC50 values of 5 nM and 1 nM for PARP-1 and PARP-2, respectively.1 In a genetically engineered mouse model for BRCA1-associated breast cancer olaparib inhibited tumor growth and improved survival with no signs of toxicity.2 Synergizes with many other anticancer agents.3 Shows efficacy in colorectal cancers.4 Prevents house dust mite allergen-induced asthma in a mouse model.5