Hinokitiol is a potent metal chelator that induces differentiation and apoptosis in teratocarcinoma F9 cells.1 It acts as a reversible inhibitor of platelet-type 12-lipoxygenase (IC50 = 100 nM).2 Reported to have strong antibacterial activity3, suppress cell growth and disrupt androgen receptor signaling4 and activate hypoxia-inducible factor5.
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