Chemical Name: 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
Mitochondrial benzodiazepine receptor ligand
Molecular Weight:
352.86
Form:
White solid
CAS Number:
[85532-75-8]
Formula:
C21H21ClN2O
Application Notes:
PK-11195 is a selective and potent peripheral benzodiazepine receptor, PBR (or TSPO, translocator protein) antagonist.1,2 It has been shown to chemosensitize tumor cells to a variety of chemotherapeutic agents via PBR-independent pathways.3,4 PK11195 is also able to induce apoptosis in a variety of cell lines.5-7
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