Chemical Name: N-(3,4-Dimethoxycinnamoyl)anthranilic acid. Alternate Names: Rizaben
NFkappaB inhibitor
Molecular Weight:
327.34
Purity:
98% by TLC, NMR (Conforrms)
Form:
Pale yellow solid
CAS Number:
[53902-12-8]
Formula:
C18H17NO5
Application Notes:
Tranilast is an anti-allergy agent (inhibition of mast cell degranulation) that has been shown to have potent immunomodulatory effects (via inhibition of endotoxin induced: PGE2, IC50 = 1-20 µM, TXB2, IC50 = 10-50 µM, TGFbeta1, IC50 = 100-200 µM, IL-8, IC50 = 100 µM) .1,2,3 Tranilast also displays anti-angiogenic properties.4,5
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