Chemical Name: (2S)-1-(3-Mercapto-2-methyl-propionyl)-L-proline
Angiotensin-converting enzyme inhibitor
Molecular Weight:
217.28
Purity:
98% by HPLC, NMR (Conforms)
Form:
White solid
CAS Number:
[62571-86-2]
Formula:
C9H15NO3S
Application Notes:
Captopril is an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 µM).1 Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and competitively (Ki = 6.0 µM for leukotriene B4 formation and Ki = 60 nM for L-lysine-p-nitroanilide).2 Displays vasodilatory and antihypertensive effects in vivo. Clinically useful antihypertensive agent.
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