Chemical Name: S(+)-N,N-Diethyl-N'([8alpha]-6-methylergolin-8-yl)urea. Alternate Names: S(+)-Terguride
Dopamine D2 agonist
Molecular Weight:
340.47
Purity:
98% by TLC, NMR (conforms)
Form:
White solid
CAS Number:
[37686-84-3]
Formula:
C20H28N4O
Application Notes:
A semi-synthetic ergoline derivative which acts as a partial dopamine D2 agonist and 5HT2B/2C receptor antagonist. Displays antiparkinsonian effects in MPTP-treated cynomolgus monkeys1. Partial agonist at recruitment of -arrestin2 to the D2 receptor2. Ameliorates monocrotaline-induced pulmonary hypertension in rats3.
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