Chemical Name: 3-(Endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane methanesulfonate
Induces remyelination of neurons
Molecular Weight:
403.53
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[132-17-2]
Formula:
C21H25NO CH4SO3
Application Notes:
Centrally acting M1 muscarinic acetylcholine receptor antagonist (Ki=0.59 nM, rat).1 Also inhibits the dopamine transporter (Ki=160 nM).2 Enhances remyelination and significantly decreases clinical severity in the experimental autoimmune encephalomyelitis model of relapsing-remitting multiple sclerosis alone or in combination with immunosuppressive agents.3 Inhibits hepatitis C virus infection.4
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