SB-216763, CAS [[280744-09-4]]
Catalog Number:
FBM-10-2338
| Article Name: |
SB-216763, CAS [[280744-09-4]] |
| Biozol Catalog Number: |
FBM-10-2338 |
| Supplier Catalog Number: |
10-2338 |
| Alternative Catalog Number: |
FBM-10-2338-5MG, FBM-10-2338-25MG |
| Manufacturer: |
Focus Biomolecules |
| Category: |
Biochemikalien |
| Alternative Names: |
Chemical Name: 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Molecular Weight: |
371.23 |
| Purity: |
98% by TLC [1% CH3OH in CH2Cl2, Rf = 0.17] NMR (Conforms) |
| Form: |
Orange solid |
| CAS Number: |
[280744-09-4] |
| Formula: |
C19H12Cl2N2O2 |
| Application Notes: |
Potent and selective inhibitor of glycogen synthase kinase-1 (GSK-3) IC50=34.3 nM1. Acts at the ATP-binding domain. Displays protective effects in lung fibrosis mouse model2. Displays neuroprotective effects on cultured neurons3. Maintains mouse embryonic stem cells in a pluripotent state4. Cell permeable. |
