Jervine, CAS [[469-59-0]]

Product Overview

• Article Name: Jervine, CAS [[469-59-0]]
• Biozol Catalog Number: FBM-10-2388
• Supplier Catalog Number: 10-2388
• Alternative Catalog Number: FBM-10-2388-5MG, FBM-10-2388-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (3beta,23beta)-17,23-Epoxy-3-hydroxyveratraman-11-one. Alternate Names: 11-Ketocyclopamine

Product Description

Hedgehog pathway

Product Properties

• Molecular Weight: 425.62
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [469-59-0]
• Formula: C27H39NO3

Application Notes

• Application Notes: Inhibitor of Hedgehog signaling (IC50 = 0.5-0.7 µM). Binds directly to Smoothened (Smo)1. Inhibits the response of target tissues to Sonic hedgehog signaling2. Induces COX-2 overexpression in human erythroleukemia cells3.