PJ-34 HCl, CAS [[344458-15-7]]

Product Overview

• Article Name: PJ-34 HCl, CAS [[344458-15-7]]
• Biozol Catalog Number: FBM-10-2395
• Supplier Catalog Number: 10-2395
• Alternative Catalog Number: FBM-10-2395-5MG,FBM-10-2395-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride

Product Description

PARP1,2 inhibitor

Product Properties

• Molecular Weight: 331.81
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [344458-15-7]
• Formula: C17H17N3O2

Application Notes

• Application Notes: A potent and selective inhibitor of PARP1 and 2. EC50 = 20 nM1. Reduces ischemia reperfusion injury in a mouse model.2 Displays anti-inflammatory effects in a transient focal cerebral ischemia mouse model.3 Causes PARP1 independent, p21 dependent mitotic arrest.4

Images

10-2395