An adenosine analog lacking the hydroxyl at the 3 position. Inhibits PARP1 and polyadenylation2. Displays anti-inflammatory effects1,3 and neuroprotective effects by inhibiting A-induced apoptosis in hippocampal neurons4. Induces apoptosis in a variety of cancer cell lines5. Displays antiobesity effects.6 Inhibits cell senescence via activation of AMPK.7 Maintains stem cell pluripotency and increases iPS cell generation efficiency.8
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