Chemical Name: (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol
Glycosidase inhibitor
Molecular Weight:
163.17
Purity:
98% by TLC, NMR (conforms)
Form:
White solid
CAS Number:
[19130-96-2]
Formula:
C6H13NO4
Application Notes:
Inhibits alpha-glucosidase I and II1,2. Inhibits human immunodeficiency virus envelope glycoprotein-mediated membrane fusion at the CXCR4 binding step3. May be used to produce an affinity ligand for purifying glucosidase 14. Was used to inhibit ER glucosidases I and II allowing for the discovery of a second mechanism for deglucosylation of N-linked oligosaccharides in PhaR1.7, a mouse lymphoma cell line5.
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