Artesunate, CAS [[88495-63-0]]

Product Overview

• Article Name: Artesunate, CAS [[88495-63-0]]
• Biozol Catalog Number: FBM-10-2411
• Supplier Catalog Number: 10-2411
• Alternative Catalog Number: FBM-10-2411-100MG,FBM-10-2411-500MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Kills cancer stem cells / Depolarizes mitochondria

Product Properties

• Molecular Weight: 384.42
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [88495-63-0]
• Formula: C19H28O8

Application Notes

• Application Notes: A semisynthetic derivative of the natural product artemisinin which is clinically useful for treatment of malaria and other parasitic diseases. Depolarizes mitochondrial the membrane via generation of reactive oxygen species which disrupt the electron transport chain.1 Generation of mitochondrial ROS is dependent on RIP1.2 Inhibits TNFalpha-induced production of proinflammatory cytokines in human RA fibroblast-like synoviocytes.3 Displays cytotoxicity against a variety of cancer cells4 and cancer stem cells5.