SB-431542, CAS [[301836-41-9]]

Product Overview

• Article Name: SB-431542, CAS [[301836-41-9]]
• Biozol Catalog Number: FBM-10-2443
• Supplier Catalog Number: 10-2443
• Alternative Catalog Number: FBM-10-2443-5MG, FBM-10-2443-25MG, FBM-10-2443-10MM/1MLDMSO
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide

Product Description

ALK4,5 and 7 inhibitor

Product Properties

• Molecular Weight: 384.40
• Purity: 99% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [301836-41-9]
• Formula: C22H16N4O3

Application Notes

• Application Notes: Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFbeta superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM)1,2. Inhibits TGFbeta-induced proliferation of human osteosarcoma cells3. Ehances growth and integrity of embryonic stem cell-derived endothelial cells4. A frequently used agent employed in numerous stem cell differentiation protocols5. Cell permeable.