THI, CAS [[94944-70-4]]

Product Overview

• Article Name: THI, CAS [[94944-70-4]]
• Biozol Catalog Number: FBM-10-2477
• Supplier Catalog Number: 10-2477
• Alternative Catalog Number: FBM-10-2477-5MG, FBM-10-2477-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-Acetyl-4-tetrahydroxybutyl Imidazole. Alternate Names: 1-[5-[(1R,2S,3R)-1,2,3,4-tetrahydroxybutyl]-1H-imidazol-2-yl]-ethanone

Product Description

Immunomodulator (S1P lyase inhibition)

Product Properties

• Molecular Weight: 230.22
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [94944-70-4]
• Formula: C9H14N2O5

Application Notes

• Application Notes: THI was identified as a biologically active impurity in caramel food coloring.1 It is a potent inhibitor of sphingosine-1-phosphate (S1P) lyase.2 It disrupts lymphocyte egress from lymphoid tissue by interfering with S1P gradients.3,4 The novel immunomodulatory activity of THI and its biochemical mechanism may represent a new target for the development of new generation of immunosuppressants.5