TTNPB, CAS [[71441-28-6]]

Product Overview

• Article Name: TTNPB, CAS [[71441-28-6]]
• Biozol Catalog Number: FBM-10-2517
• Supplier Catalog Number: 10-2517
• Alternative Catalog Number: FBM-10-2517-5MG,FBM-10-2517-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Ro 13-7410, AGN-191183, Arotinoid acid

Product Description

Retinoic RAR agonist

Product Properties

• Molecular Weight: 348.49
• Purity: >98% by HPLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [71441-28-6]
• Formula: C24H28O3

Application Notes

• Application Notes: Highly potent and selective retinoic acid analog acting as an RAR agonist (EC50 = 21, 4 and 2.4 nM for RARalpha, RARbeta and RARgamma respectively).1 TTNPB has been extensively used in stem cell differentiation protocols. It enhances reprogramming efficiency in chemically induced pluripotent stem cells.2 Chondrocytes are robustly induced from human pluripotent stem cells by treatment with CHIR99021 and TTNPB.3 TTNPB alone, efficiently converts primary adult mouse fibroblasts into dermal papilla cell-like cells.4 Can be used in combination with other small molecules for induction of mouse totipotent stem cells.5