Chemical Name: 4,4-Pentamethylene-2-pyrrolidone. Alternate Names: GBP-L
Neuroprotective agent
Molecular Weight:
153.22
Purity:
98% by TLC, NMr (Conforms)
Form:
White solid
CAS Number:
[64744-50-9]
Formula:
C9H15NO
Application Notes:
Reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntingtons disease.1 Displays neurotrophic effects, enhancing the formation of dendritic filopodia and inducing a network of F-actin-containing neurites in cultured hippocampal neurons.2 Promotes the survival of cultured central nervous system neurons possibly by opening mitochondrial KATP channels.3 Displays neuroprotective effects in a rat model of acute retinal ischemia.4
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