Chemical Name: (S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid. Alternate Names: N-Phthalyl-L-tryptophan
DNA Methyltransferase inhibitor
Molecular Weight:
334.34
Purity:
98% by TLC, NMr (Conforms)
Form:
Tan solid
CAS Number:
[48208-26-0]
Formula:
C19H14N2O4
Application Notes:
A non-nucleoside DNA methyltransferase inhibitor. IC50=115 nM1 Inhibits DNA methylation in human tumor cell lines without toxicity2. Enhances the reversion of neural progenitor cells to the pluripotent state3.
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