Chemical Name: [4S-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a,tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
Neuroprotective, antiapoptotic
Molecular Weight:
493.95
Purity:
98% by TLC, NMR (Conforms)
Form:
yellow solid
CAS Number:
[13614-98-7]
Formula:
C23H27N3O7 HCl
Application Notes:
Displays antiapoptotic, anti-inflammatory1 activity. Prevents neuropathic pain in a rat sciatic nerve injury model1. Reduces MMP-9 activity2. Attenuates disease severity in mouse models of multiple sclerosis3. Displays neuroprotective activity4. May be effective in methotrexate-induced lung fibrosis5. Orally active and brain penetrant.
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