Chemical Name: N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide. Alternate Names: OPC-3689
PDE3 inhibitor
Molecular Weight:
342.44
Purity:
98% by HPLC, NMR (Conforms)
Form:
White solid
CAS Number:
[68550-75-4]
Formula:
C20H26N2O3
Application Notes:
Selective inhibitor of phosphodiesterase-3 (PDE3). Displays limited selectivity for PDE3A versus PDE3B (IC50 = 27 and 50 nM)1,2. Blocks PKB/Akt signaling pathway downstream via inhibition of Akt-activated PDE3B3. Reverses the effect of leptin on food intake and body weight4.
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