SirtAct, CAS [[839699-72-8]]

Product Overview

• Article Name: SirtAct, CAS [[839699-72-8]]
• Biozol Catalog Number: FBM-10-2595
• Supplier Catalog Number: 10-2595
• Alternative Catalog Number: FBM-10-2595-5MG,FBM-10-2595-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: CAY10591

Product Description

Sirt1 activator

Product Properties

• Molecular Weight: 367.46
• Purity: 98% by TLC, NMR (Conforms)
• Form: Olive green solid
• CAS Number: [839699-72-8]
• Formula: C20H25N5O2

Application Notes

• Application Notes: Sirt1 activator (233% at 10 µM)1 Suppresses TNFalpha release from THP-1 cells and stimulates adipogenesis in 3T3L1 cells1. SIRT1 stimulation by SirtAct leads to decreased tissue factor mediated thrombogenicity in mice2. Inhibits NFkappaB activation and reduces inflammatory cytokine production in lamina propria mononuclear cells from IBD patients3. Prevents and cures experimental colitis in a mouse model3.