Montelukast sodium, CAS [[151767-02-1]]
Catalog Number:
FBM-10-2597
| Article Name: |
Montelukast sodium, CAS [[151767-02-1]] |
| Biozol Catalog Number: |
FBM-10-2597 |
| Supplier Catalog Number: |
10-2597 |
| Alternative Catalog Number: |
FBM-10-2597-50MG, FBM-10-2597-250MG |
| Manufacturer: |
Focus Biomolecules |
| Category: |
Biochemikalien |
| Alternative Names: |
Chemical Name: 2-[1-[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetate, sodium salt. Alternate Names: MK-0476 |
| Leukotriene CysLT1 antagonist and GPR17 antagonist |
| Molecular Weight: |
608.17 |
| Purity: |
98% by HPLC, NMR (Conforms) |
| Form: |
Solid |
| CAS Number: |
[151767-02-1] |
| Formula: |
C35H35ClNO3S Na |
| Application Notes: |
Potent, selective CysLT1 receptor (leukotriene D4) antagonist (Ki = 0.18 nM).1,2 Displays anti-inflammatory and anti-asthmatic effects. Clinically useful agent for treatment of chronic asthma.3 Attenuates chronic brain injury after focal cerebral ischemia in rodent models.4 Decreases blood brain barrier dysfunction in mouse models.5 Blockade of GPR17 by montelukast elevates neural stem and progenitor proliferation.6 |
