Alternate Names: Fermentation product of Aspergillus fumigatus
Neuritogenic activity
Molecular Weight:
431.44
Purity:
99% by TLC/HPLC NMR (conforms)
Form:
White solid
CAS Number:
[58523-30-1]
Formula:
C22H25NO8
Application Notes:
A fungal metabolite with novel structure. Displays potent neuritogenic activity in PC12 cells. Induces multipolar and branching neurites comparable to that produced by -NGF.1 Displays immunosuppressive activity via inhibition of immunoglobulin E production in vitro.2 Displays antiproliferative effects on four glioma cell lines by regulating tumor metabolic enzymes.3 Inhibits osteoclastogenesis and prevents ovariectomized-induced bone loss by suppression of ROS.4
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