Chemical Name: beta-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid. Alternate Names: beta-Anthraniloyl-L-alanine
Endogenous Ahr agonist
Molecular Weight:
208.22
Purity:
98% by HPLC, NMR (Conforms)
Form:
Off-white solid
CAS Number:
[2922-83-0]
Formula:
C10H12N2O3
Application Notes:
Tryptophan catabolite1. Endogenous tumor-promoting ligand of the human aryl hydrocarbon receptor (AhR). Constitutively generated by human tumor cells via the action of the tryptophan degrading enzyme, tryptophan-2,3-dioxygenase (TDO). Kynurenine suppresses antitumor immune responses and promotes tumor cell survival and motility2.
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