Metabolite of fluoxetine.3 Induces long QT syndrome via slow delayed rectifier potassium current block.1 Time dependent inhibitor of CYP2C19 and CYP3A4.2 The S-isomer of desmethylfluoxetine is the active N-demethylated metabolite responsible for the persistently potent and selective inhibition of serotonin uptake in vivo.3 Potent inhibitor of coxsackievirus replication acting via inhibition of viral RNA synthesis.4 State-dependent TREK-2 blocker.5
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