Chemical Name: 3-Phenyl-3-(4-trifluoromethyl-phenoxy)-propylamine hydrochloride (racemic). Alternate Names: Desmethylfluoxetine
Fluoxetine metabolite
Molecular Weight:
331.76
Purity:
98% by TLC NMR (Conforms)
Form:
Beige waxy solid
CAS Number:
[57226-68-3]
Formula:
C16H16F3NO HCl
Application Notes:
Metabolite of fluoxetine.3 Induces long QT syndrome via slow delayed rectifier potassium current block.1 Time dependent inhibitor of CYP2C19 and CYP3A4.2 The S-isomer of desmethylfluoxetine is the active N-demethylated metabolite responsible for the persistently potent and selective inhibition of serotonin uptake in vivo.3 Potent inhibitor of coxsackievirus replication acting via inhibition of viral RNA synthesis.4 State-dependent TREK-2 blocker.5
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