Chemical Name: (3R,11bR)-rel-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one
VMAT2 inhibitor
Molecular Weight:
317.43
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[58-46-8]
Formula:
C19H27NO3
Application Notes:
Potent inhibitor of the vesicular monoamine transporter (VMAT), IC50=3.2 nM1,2 with selectivity for VMAT2 over VMAT13. Promotes late stage differentiation of Pdx1-positive pancreatic progenitor cells into Neurog3-positive endocrine precursors4.
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