Chemical Name: alpha-Amino-3-hydroxy-5-isoxazoleacetic acid hydrate
NMDA and m GluR agonist
Molecular Weight:
176.13
Purity:
98% by TLC NMR (Conforms)
Form:
White solid
CAS Number:
[2552-55-8]
Formula:
C5H6N2O4H2O
Application Notes:
Ibotenic acid is a conformationally restricted analog of glutamate which occurs naturally in Amanita mascaria and related mushrooms. It is a non-specific glutamate receptor (both NMDA and mGluR) agonist.1 May be used to induce hippocampal lesioning in rat neurodegeneration models.2,3 Induces lesions in the subiculum in a mouse model of Alzheimers disease.4
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