Chemical Name: 1-[4-Amino-2-ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol. Alternate Names: R848
TLR7/8 agonist / Immune adjuvant
Molecular Weight:
314-38
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[144875-48-9]
Formula:
C17H22N4O2
Application Notes:
A Toll-like receptor 7/8 agonist.1 May be used as an immune adjuvant in cancer vaccines.2 Resiquimod-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.3 Topical treatment of wild-type mice induces systemic autoimmune disease which may be used as a model of systemic Lupus erythematosus.4
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