Chemical Name: 3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic acid. Alternate Names: Bongkrek acid
MPT pore opening inhibitor
Molecular Weight:
486.60
Purity:
>97% by HPLC, NMR (Conforms)
Form:
Supplied as 1mg/ml solution in Tris buffer
CAS Number:
[11076-19-0]
Formula:
C28H38O7 (free acid)
Application Notes:
A potent inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT)1. Inhibits mitochondrial permeability transition pore opening2,3. Delivery of bongkrekic acid to the mitochondria prevents apoptosis in HeLa cells4.
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