Chemical Name: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one
NFkappaB inhibitor
Molecular Weight:
270.29
Purity:
98% by HPLC, NMR (Conforms)
Form:
Yellow solid
CAS Number:
[19309-14-9]
Formula:
C16H14O4
Application Notes:
Inhibits NF-kappaB activation via inhibition of IkappaBalpha degradation and phosphorylation, IkappaB kinase activation and NF-kappaB nuclear translocation1,2. Displays anti-inflammatory activity in various models3. Cell permeable.
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