Chemical Name: 3alpha,7beta-Dihydroxy-5beta-cholan-24-oic acid N-(2-sulfoethyl)amide. Alternate Names: Tauroursodeoxycholic acid
ER stress inhibitor
Molecular Weight:
521.69
Purity:
95% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[14605-22-2]
Formula:
C26H44NO6SNa
Application Notes:
A classic inhibitor of endoplasmic reticulum (ER) stress.1 Reduces ER stress and adipose tissue inflammation in a mouse model of high fat diet-induced obesity.2 Blocks ER stress-induced NLRP3 inflammasome activation and hepatocyte death.3 Attenuates amyloid precursor protein processing and amyloid-beta deposition in APP/PS1 mouse model.4
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