Chemical Name: N-(5-Aminopentyl)-5-dimethylaminonaphthalene-1-sulfonamide. Alternate Names: Monodansyl cadaverine, MDC
Autophagic vacuole dye
Molecular Weight:
335.46
Purity:
97% by TLC, NMR (Conforms)
Form:
Off-white solid
CAS Number:
[10121-91-2]
Formula:
C17H25N3O2S
Application Notes:
MDC preferentially accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids making it a very useful probe for monitoring autophagy.1,2 Inhibits EGF internalization.3 Competes with certain trans-aminases and can be used with antibody/affinity procedures to isolate resulting conjugates.4 Abs: 335 nm, Em: 510 nm
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