DPN, CAS [[1428-67-7]]

Product Overview

• Article Name: DPN, CAS [[1428-67-7]]
• Biozol Catalog Number: FBM-10-2909
• Supplier Catalog Number: 10-2909
• Alternative Catalog Number: FBM-10-2909-5MG, FBM-10-2909-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2,3-bis(4-Hydroxyphenyl)-propionitrile. Alternate Names: Diarylpropionitrile

Product Description

Estrogen ERbeta agonist

Product Properties

• Molecular Weight: 239.27
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1428-67-7]
• Formula: C15H13NO2

Application Notes

• Application Notes: Potent estrogen ERbeta receptor agonist. Displays a 70-fold selectivity over ERalpha, EC50 = 0.85 and 66 nM, respectively.1 Regulates expression of GluR1, 2 and 3 in rat hippocampus.2 Ameliorates portal hypertension in a carbon tetrachloride-induced liver cirrhosis rat model.3 Stimulates proliferation of androgen-independent prostate cancer cell line PC-3 via a novel pathway involving ERbeta-mediated activation of beta-catenin.4 A useful tool for elucidating the biological function of ERbeta.5