Cinacalcet HCl, CAS [[364782-34-3]]

Product Overview

• Article Name: Cinacalcet HCl, CAS [[364782-34-3]]
• Biozol Catalog Number: FBM-10-2957
• Supplier Catalog Number: 10-2957
• Alternative Catalog Number: FBM-10-2957-10MG,FBM-10-2957-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: AMG 073, KRN 1493, Mimpara, Sensipar

Product Description

Calcium sensing receptor (CaSR) agonist

Product Properties

• Molecular Weight: 393.88
• Purity: >98% by TLC NMR (Conforms)
• Form: White solid
• CAS Number: [364782-34-3]
• Formula: C22H22F3N HCl

Application Notes

• Application Notes: Cinacalcet (364782-34-3) is a calcimimetic that allosterically activates the calcium-sensing receptor (CaSR, EC50 = 79.4 nM in HEK 293T cells expressing CaSR).1-3 It lowers plasma parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism.4 Cinacalcet has been used to treat parathyroid carcinoma.5