(5Z)-7-Oxozeaenol, CAS [[253863-19-3]]

Catalog Number: FBM-10-3023
Article Name: (5Z)-7-Oxozeaenol, CAS [[253863-19-3]]
Biozol Catalog Number: FBM-10-3023
Supplier Catalog Number: 10-3023
Alternative Catalog Number: FBM-10-3023-1MG, FBM-10-3023-5MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: (3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
TAK1 inhibitor
Molecular Weight: 362.38
Purity: >98% by HPLC NMR (Conforms)
Form: White to off-white solid
CAS Number: [253863-19-3]
Formula: C19H22O7
Application Notes: Potent and selective inhibitor of TAK1 (mitogen activated protein kinase kinase kinase) IC50 = 8 nM.1 Selective over MEKK1 and MEKK4. Blocks IL-1-induced activation of TAK1 in cell culture.1 Blocks the production of pro-inflammatory cytokines and displays anti-inflammatory activity in various models.2-4