ALLN, CAS [[110044-82-1]]

Product Overview

• Article Name: ALLN, CAS [[110044-82-1]]
• Biozol Catalog Number: FBM-10-3024
• Supplier Catalog Number: 10-3024
• Alternative Catalog Number: FBM-10-3024-5MG, FBM-10-3024-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Ac-Leu-Leu-Nle-CHO. Alternate Names: Ac-LL-norleucinal, Ac-Leu-Leu-Nle-CHO

Product Description

Calpain inhibitor

Product Properties

• Molecular Weight: 383.53
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [110044-82-1]
• Formula: C20H37N3O4

Application Notes

• Application Notes: Cell-permeable, peptide aldehyde inhibitor of calpain I (Ki=190 nM), calpain II (Ki=150 nM), cathepsin L (Ki=0.5 nM) and other neutral cysteine proteases.1 Inhibits cell cycle progression at G1/S and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation.2 Inhibits proteolytic degradation of IkappaBalpha and IkappaBbeta in RAW macrophages induced with LPS.3 Blocks AIF-mediated necroptosis.4 Cell permeable.