A nitric oxide (NO) scavenger. Carboxy-PTIO (148819-94-7) reacts with NO with 1:1 stoichiometry1 producing NO2-/NO3-. In LPS-induced endotoxin shock, carboxy-PTIO reversed hypotension and renal dysfunction and increased survival in a rat model.2 A very useful tool for probing the involvement of NO in physiological processes.3,4
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