Chemical Name: 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, potassium salt. Alternate Names: Carboxy-PTIO, c-PTIO
Nitric oxide scavenger
Molecular Weight:
315.39
Purity:
98% by HPLC, NMR (Conforms)
Form:
Blue solid
CAS Number:
[148819-94-7]
Formula:
C14H16KN2O4
Application Notes:
A nitric oxide (NO) scavenger. Carboxy-PTIO (148819-94-7) reacts with NO with 1:1 stoichiometry1 producing NO2-/NO3-. In LPS-induced endotoxin shock, carboxy-PTIO reversed hypotension and renal dysfunction and increased survival in a rat model.2 A very useful tool for probing the involvement of NO in physiological processes.3,4
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