Chemical Name: (7S,13E, 16S, 17E, 19R, 21E)-6,7-Epoxy-19-hydroxy-10-(1H-indol-3-yl)-16,18-dimethyl-[13]cytochalasa- 13,17,21-triene-1,20,23-trione
Actin binding agent / Apoptosis inducer
Molecular Weight:
528.64
Purity:
98% by HPLC, NMR (Conforms)
Form:
Yellow solid
CAS Number:
[50335-03-0]
Formula:
C32H36N2O5
Application Notes:
A cytochalasin analog which targets filamentous actin. Displays cytotoxic effects against human colorectal HCT116 cells, IC50=3.15 µM.1 Preferentially induces apoptosis in chronic lymphocytic leukemia cells via targeting the cytoskeleton.2 Enhances the fibrinolytic activity of vascular endothelial cells.3
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