Ophiobolin, CAS [[4611-05-6]]

Product Overview

• Article Name: Ophiobolin, CAS [[4611-05-6]]
• Biozol Catalog Number: FBM-10-3150
• Supplier Catalog Number: 10-3150
• Alternative Catalog Number: FBM-10-3150-200UG, FBM-10-3150-1MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Alternate Names: Cochliobolin A, Ophiobalin, NSC 114340

Product Description

Autophagy inducer / Anticancer

Product Properties

• Molecular Weight: 400.55
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [4611-05-6]
• Formula: C25H36O4

Application Notes

• Application Notes: Selectively inhibits the growth of cancer cells (IC50=0.4-4.3 M) over normal cells (IC50=20.9 M).1 Induces non-apoptotic cell death in glioblastoma cells and is active in an in vivo model.2 Covalently reacts with primary amines such as lysine side chains2 and phosphatidylethanolamine3 forming unique pyrrole adducts. Induces ER stress4, paraptosis4 and autophagy5.