Chemical Name: 4-guanidinobutyl 4-hydroxy-3,5-dimethoxybenzoate. Alternate Names: SCM-198
Neuroinflammation inhibitor
Molecular Weight:
311.33
Purity:
98% by TLC NMr (Conforms)
Form:
white solid
CAS Number:
[24697-74-3]
Formula:
C14H21N3O5
Application Notes:
Inhibits microglial overactivation and attenuates Abeta(1-40)-induced cognitive impairments in rats via JNK and NF-kappaB pathways.1 Inhibits the formation of advanced glycation end products.2 Ameliorates cognitive dysfunction by antagonizing exocytotoxic glutamate insults and inhibiting autophagy.3 Attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4.4 Attenuates early atherosclerotic lesions in hypercholest-erolemic rabbits via modulation of the inflammatory and oxidative stress pathways.5
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