Chemical Name: Cholest-4-en-3-one oxime. Alternate Names: Olesoxime
Neurotrophic agent
Molecular Weight:
399.65
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[22033-87-0]
Formula:
C27H45NO
Application Notes:
Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP).1 Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in a mouse model of intracerebral hemorrhage.2 Inhibits MPTP opening and protects neurons from apoptosis.3 Induces oligodendrocyte maturation in culture and promotes myelin regeneration in vivo in a rodent model.4
10-3230
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