2-AAPA, CAS [[1133387-90-2]]

Product Overview

• Article Name: 2-AAPA, CAS [[1133387-90-2]]
• Biozol Catalog Number: FBM-10-3238
• Supplier Catalog Number: 10-3238
• Alternative Catalog Number: FBM-10-3238-5MG, FBM-10-3238-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: R,R'-2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylthiocarbonylamino)-phenylthiocarbamoylsulfanyl]propionic acid, hydrate

Product Description

Glutathione and thioredoxin reductase inhibitor

Product Properties

• Molecular Weight: 518.65
• Purity: 98% by HPLC
• Form: White or off-white solid
• CAS Number: [1133387-90-2]
• Formula: C18H22N4O6S4

Application Notes

• Application Notes: Inhibits glutathione reductase and thioredoxin reductase,IC50s=6.7 and 8.7 µM respectively, and impairs mitochondrial function.1 May be used to induce a cellular model of thiol oxidative stress.2 Enhances sensitivity of cancer cell lines to X-ray irradiation.3 Induces G2/M cell cycle arrest by inducing thiol oxidative stress resulting in alpha-tubulin S-glutathionylation-mediated microtubule depolymerization.4 Improves limb revascularization by glutathionylation and subsequent stabilization of HIF-1alpha.5