Hymeglusin, CAS [[29066-42-0]]

Product Overview

• Article Name: Hymeglusin, CAS [[29066-42-0]]
• Biozol Catalog Number: FBM-10-3289
• Supplier Catalog Number: 10-3289
• Alternative Catalog Number: FBM-10-3289-1MG, FBM-10-3289-2.5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 11-[3R-(Hydroxymethyl)-4-oxo-2R-oxetanyl]-3,5,7R-trimethyl-2E,4E-undecadienoic acid. Alternate Names: L-659699, Antibiotic 1233A, Antibiotic F244

Product Description

Melvalonate biosynthesis inhibitor

Product Properties

• Molecular Weight: 324.41
• Purity: 96% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [29066-42-0]
• Formula: C18H28O5

Application Notes

• Application Notes: Inhibitor of eukaryotic mevalonate biosynthesis via inhibition of HMG-CoA synthase, IC50=0.12 µM.1 Acts via covalent modification of the active site Cys129.1,2 Inhibits cholesterol biosynthesis in rats (45% at 25 mg/Kg),1 Also inhibits bacterial HMG-CoA synthase.3 Inhibits dengue virus replication.4