Chemical Name: 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Alternate Names: Sapanisertib, MLN0128, TAK-228
TORC1/2 inhibitor
Molecular Weight:
309.33
Purity:
98% by TLC/HPLC NMR (Conforms)
Form:
Off-white solid
CAS Number:
[1224844-38-5]
Formula:
C15H15N7O
Application Notes:
A potent and selective, ATP-competitive inhibitor of mTOR kinase, Ki = 1.4 nM.1 Inhibits growth and proliferation of various breast cancer cell lines and human endothelial cells.2
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