VGX1027, CAS [[6501-72-0]]

Product Overview

• Article Name: VGX1027, CAS [[6501-72-0]]
• Biozol Catalog Number: FBM-10-3409
• Supplier Catalog Number: 10-3409
• Alternative Catalog Number: FBM-10-3409-20MG, FBM-10-3409-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid. Alternate Names: GIT 27

Product Description

Immunomodulator cytokine release inhibitor

Product Properties

• Molecular Weight: 205.2
• Purity: 98% by HPLC
• Form: White solid
• CAS Number: [6501-72-0]
• Formula: C11H11NO3

Application Notes

• Application Notes: Immunomodulator. Inhibits secretion of IL-1beta, TNF-alpha, and IL-10 from murine macrophages stimulated with LPS and spares T cell function.1 Ameliorates the course of acute and chronic immunoinflammatory conditions such as carrageenan-induced pleurisy, LPS-induced lethality and type II collagen-induced arthritis in mouse models.1 Prevents spontaneous and accelerated forms of autoimmune diabetes in a NOD mouse model.2 Moldulates genes involved in LPS-induced Toll-like receptor 4 activation in a mouse Lupus model.3 Displays protective effects in particulate matter-induced acute lung injury by blocking TLR4 signaling.4