Chemical Name: Sesquiterpenoid isolated from Inula viscosa
NFkB activation inhibitor
Molecular Weight:
248.32
Purity:
97% by HPLC NMR (Conforms)
Form:
Yellow oil
CAS Number:
[33649-15-9]
Formula:
C15H20O3
Application Notes:
Extracts of Inula which contain tomentosin have been used for centuries in traditional medicine for the treatment of inflammation.1 It suppresses the production of inflammatory mediators in RAW264.7 cells by inhibiting NFB activation.2 It induces telomere shortening and caspase-dependent apoptosis in cervical cancer cells3 and induces apoptosis in human osteosarcoma MG-63 cells4. It causes G2/M arrest and apoptosis in human melanoma cell lines.5
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