R-59022, CAS [[93076-89-2]]

Product Overview

• Article Name: R-59022, CAS [[93076-89-2]]
• Biozol Catalog Number: FBM-10-3579
• Supplier Catalog Number: 10-3579
• Alternative Catalog Number: FBM-10-3579-5MG, FBM-10-3579-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one. Alternate Names: Diacylglycerol kinase inhibitor i

Product Description

DAG Kinase inhibitor

Product Properties

• Molecular Weight: 459.58
• Purity: 98% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [93076-89-2]
• Formula: C27H26FN3OS

Application Notes

• Application Notes: R-59022 is a diacylglycerol kinase (DAGK) inhibitor, nonselective for DAGK isotypes (IC50=2.8 µM in intact platelets).1 Induces autophagy and apoptosis in NG108-15 neuronal cells via an mTOR-independent mechanism.2 Prevents conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes.3 Blocks filovirus internalization in host cells.4