CBA, CAS [[351424-20-9]]

Product Overview

• Article Name: CBA, CAS [[351424-20-9]]
• Biozol Catalog Number: FBM-10-3643
• Supplier Catalog Number: 10-3643
• Alternative Catalog Number: FBM-10-3643-5MG, FBM-10-3643-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid. Alternate Names: TRPM4-IN-5

Product Description

TRPM4 blocker

Product Properties

• Molecular Weight: 340.16
• Purity: >98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [351424-20-9]
• Formula: C15H11Cl2NO4

Application Notes

• Application Notes: CBA is a selective blocker of TRPM4 channels (IC50 = 1.5 mM) with no activity at TRPM5, TRPM7, TRPM8, TRPV1, TRPV3, TRPV6 and a panel of other ion channels and receptors.1 Displays protective effects in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration.2 A highly useful tool for exploring the functions of TRM4 in a variety of cell types.3,4