Eltrombopag, CAS [[496775-61-2]]

Product Overview

• Article Name: Eltrombopag, CAS [[496775-61-2]]
• Biozol Catalog Number: FBM-10-3768
• Supplier Catalog Number: 10-3768
• Alternative Catalog Number: FBM-10-3768-5MG, FBM-10-3768-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-[2-[(2Z)-1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid. Alternate Names: SB-497115

Product Description

Thrombopoietin agonist

Product Properties

• Molecular Weight: 442.47
• Purity: 98% by TLC NMR (Conforms)
• Form: Orange solid
• CAS Number: [496775-61-2]
• Formula: C25H22N4O4

Application Notes

• Application Notes: A novel, orally active, small molecule human thrombopoietin receptor (TPO-R) agonist, EC50=0.27 M.1,2 Maintains human hematopoietic stem and progenitor cells under inflammatory conditions.3 Promotes DNA repair in human hematopoietic stem and progenitor cells.4 Acts as a powerful chelator of cellular and extracellular iron(III).5 Stimulates hematopoietic stem cells via a TPO-R-independent mechanism involving iron chelation.6