Chemical Name: 7-Allyl-7,8-dihydro-8-oxoguanosine. Alternate Names: RWJ-21757
TLR7 agonist
Molecular Weight:
336.30
Purity:
96% by TLC NMR (conforms)
Form:
White solid
CAS Number:
[121288-39-9]
Formula:
C13H17N5O6
Application Notes:
Toll-like receptor 7 (TLR7) agonist.1 A potent immunostimulant with a relatively broad spectrum of immunobiological activities including upregulation of the activity of B cells, T cells, NK cells, macrophages and LAK cells.2 Induces secretion of IFN- by NK cells.3 Inhibits influenza A infection in chickens.4 Induces tumor regression by reversing Treg-induced immunosuppression.5
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